SCHEMBL25101221 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	BRD4	O60885	4/20	0.56

▸	KMT2A	Q03164	1/20	0.39

▸	GBA1	P04062	2/20	0.37

▸	MMP2	P08253	2/20	0.36

▸	MMP1	P03956	1/20	0.36

▸	MMP3	P08254	1/20	0.36

▸	MMP7	P09237	1/20	0.36

▸	MMP9	P14780	1/20	0.36

▸	MMP8	P22894	1/20	0.36

▸	FPR1	P21462	2/20	0.35

▸	FPR2	P25090	2/20	0.35

▸	CYP3A4	P08684	2/20	0.34

▸	TDP1	Q9NUW8	1/20	0.34

▸	L3MBTL1	Q9Y468	1/20	0.34

▸	USP19	O94966	1/20	0.33

▸	CYP2C19	P33261	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31441626	0.79	APEX1 (0.50)	BRD4KMT2AGBA1MMP2MMP1
SCHEMBL31441657	0.79	APEX1 (0.50)	BRD4KMT2AGBA1MMP2MMP1
SCHEMBL11623610	0.78	BRD4 (0.58)	BRD4KMT2AGBA1L3MBTL1CYP2C19
SCHEMBL13572945	0.77	CHRM2 (0.45)	BRD4KMT2AMMP2MMP1MMP3
SCHEMBL9368683	0.77	BRD4 (0.56)	BRD4KMT2AGBA1L3MBTL1CYP2C19
SCHEMBL18772284	0.76	BRD4 (0.45)	BRD4KMT2AMMP2MMP1MMP3
SCHEMBL19988429	0.76	MMP2 (0.34)	BRD4KMT2AMMP2MMP1MMP3
SCHEMBL26050596	0.76	MMP2 (0.34)	BRD4KMT2AMMP2MMP1MMP3
SCHEMBL8294536	0.75	POLB (0.58)	BRD4CYP3A4TDP1L3MBTL1
SCHEMBL28499610	0.75	BRD4 (0.54)	BRD4KMT2AGBA1L3MBTL1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023029833-A1	SOS1 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF	上海海和药物研究开发股份有限公司	2023-03-09	—	—	WO	disclosed