Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.34 |
| ▸ | MAOB | P27338 | 8/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277827 | 0.79 | CYP1A2 (0.55) | NPC1RAB9AMAPTCYP1A2LMNA | |
| SCHEMBL13636753 | 0.78 | APP (0.41) | NPC1RAB9AMAPTCYP1A2LMNA | |
| SCHEMBL779443 | 0.78 | NPC1 (0.58) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL13991702 | 0.77 | ALDH1A1 (0.47) | NPC1RAB9AMAPTCYP1A2LMNA | |
| SCHEMBL4272691 | 0.75 | ALDH1A1 (0.48) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL846398 | 0.75 | ALDH1A1 (0.47) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL11469896 | 0.74 | NPC1 (0.38) | NPC1RAB9AMAPTCYP1A2LMNA | |
| SCHEMBL156248 | 0.74 | ESR1 (0.52) | MAPTCYP1A2LMNAMAPK1ATM | |
| Ammonia Solution, Strong SCHEMBL30424700 | 0.73 | ALDH1A1 (0.46) | NPC1RAB9AMAPTLMNAMAPK1 | |
| SCHEMBL13016 | 0.73 | NPC1 (0.50) | NPC1RAB9AMAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230075221-A1 | SUBSTITUTED 1,2,4-TRIAZOLO[4,3-A]PYRIDINE DERIVATIVE AND PREPARATION METHOD, HERBICIDAL COMPOSITION AND APPLICATION THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230075221-A1 | SUBSTITUTED 1,2,4-TRIAZOLO[4,3-A]PYRIDINE DERIVATIVE AND PREPARATION METHOD, HERBICIDAL COMPOSITION AND APPLICATION THEREOF | TH, CYP4X1, CYP4B1 | NPC1 4626/4885RAB9A 3100/4885MAPT 4382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.