Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968312 | 0.93 | TLR7 (0.49) | PIM1PIM3TLR7TLR8STING1 | |
| SCHEMBL24723244 | 0.92 | TLR7 (0.54) | PIM1PIM3TLR7TLR8 | |
| SCHEMBL22359571 | 0.91 | TLR7 (0.54) | PIM1PIM3TLR7TLR8STING1 | |
| SCHEMBL3970752 | 0.90 | TLR7 (0.52) | TLR7 | |
| SCHEMBL5110579 | 0.90 | TLR7 (0.44) | TLR7TLR8GBA1 | |
| SCHEMBL1232968 | 0.89 | TLR7 (0.45) | PIM1PIM3TLR7TLR8STING1 | |
| SCHEMBL8127843 | 0.89 | BRD4 (0.48) | PIM1PIM3TLR7STING1BRD4 | |
| SCHEMBL2743673 | 0.89 | STING1 (0.45) | PIM1PIM3TLR7TLR8STING1 | |
| SCHEMBL4551314 | 0.89 | TLR7 (0.54) | TLR7 | |
| SCHEMBL14288481 | 0.88 | MEN1 (0.41) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9908880-B2 | Substituted imidazoquinolines | 4SC AG (DE) | 2018-03-06 | — | — | US | disclosed |
| US-9908880-B2 | Substituted imidazoquinolines | 4SC AG (DE) | 2018-03-06 | — | — | US | disclosed |
| EP-2386557-B1 | Novel substituted imidazoquinolines | 4SC DISCOVERY GMBH (DE) | 2018-01-10 | — | — | EP | disclosed |
| US-20170029422-A1 | NOVEL SUBSTITUTED IMIDAZOQUINOLINES | 4SC AG (DE) | 2017-02-02 | — | — | US | disclosed |
| US-20170029422-A1 | NOVEL SUBSTITUTED IMIDAZOQUINOLINES | 4SC AG (DE) | 2017-02-02 | — | — | US | disclosed |
| US-9446040-B2 | Substituted imidazoquinolines | 4SC AG (DE) | 2016-09-20 | — | — | US | disclosed |
| US-9446040-B2 | Substituted imidazoquinolines | 4SC AG (DE) | 2016-09-20 | — | — | US | disclosed |
| US-20150335636-A1 | NOVEL SUBSTITUTED IMIDAZOQUINOLINES | 4SC AG (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150335636-A1 | NOVEL SUBSTITUTED IMIDAZOQUINOLINES | 4SC AG (DE) | 2015-11-26 | — | — | US | disclosed |
| US-9073913-B2 | Substituted imidazoquinolines | 4SC AG (DE) | 2015-07-07 | — | — | US | disclosed |
| CN-1812789-A | Sulfonamide substituted imidazoquinolines | 3M INNOVATION CO LTD (US) | 2006-08-02 | — | — | CN | disclosed |
| EP-1638566-A2 | SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-03-29 | — | — | EP | disclosed |
| US-20050197358-A1 | Sulfonamide and sulfamide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2005-09-08 | — | — | US | disclosed |
| US-6924293-B2 | Sulfonamide and sulfamide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-08-02 | — | — | US | disclosed |
| US-6888000-B2 | Sulfonamide and sulfamide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-05-03 | — | — | US | disclosed |
| WO-2005003064-A2 | SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-13 | — | — | WO | disclosed |
| WO-2005003065-A2 | SULFONAMIDE SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20040132762-A1 | Sulfonamide and sulfamide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-07-08 | — | — | US | disclosed |
| US-20040106638-A1 | Sulfonamide and sulfamide substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY | 2004-06-03 | — | — | US | disclosed |
| US-6677349-B1 | INDUCE CYTOKINE BIOSYNTHESIS; ANTICARCINOGENIC AGENTS, VIRICIDES | 3M INNOVATIVE PROPERTIES COMPANY | 2004-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335636-A1 | NOVEL SUBSTITUTED IMIDAZOQUINOLINES | TLR7, TLR1, TLR4 | PIM1 1573/4885PIM3 2025/4885TLR7 1/4885 |
| US-20050197358-A1 | Sulfonamide and sulfamide substituted imidazoquinolines | IFNG, IRF3, EIF2AK2 | PIM1 130/4885PIM3 257/4885TLR7 59/4885 |
| US-20170029422-A1 | NOVEL SUBSTITUTED IMIDAZOQUINOLINES | TLR7, TLR1, TLR4 | PIM1 1573/4885PIM3 2025/4885TLR7 1/4885 |
| US-20040132762-A1 | Sulfonamide and sulfamide substituted imidazoquinolines | IFNG, IRF3, EIF2AK2 | PIM1 130/4885PIM3 257/4885TLR7 59/4885 |
| US-20040106638-A1 | Sulfonamide and sulfamide substituted imidazoquinolines | IFNG, IRF3, EIF2AK2 | PIM1 130/4885PIM3 257/4885TLR7 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.