SCHEMBL2510339

SCHEMBL2510339

Cc1cc(C(C)C)c(C)c(OC(=O)c2ccccc2)c1OC(=O)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.43
MAPT P10636 4/20 0.43
MEN1 O00255 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42
TSHR P16473 1/20 0.40
LMNA P02545 2/20 0.39
GAA P10253 2/20 0.39
POLB P06746 1/20 0.39
HTT P42858 1/20 0.39
BCL2 P10415 1/20 0.39
MCL1 Q07820 1/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
NPBWR1 P48145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15284052 1.00 KMT2A (0.43) KMT2AMAPTMEN1TDP1GABRA1
SCHEMBL2508287 0.87 KMT2A (0.42) KMT2AMAPTMEN1TDP1GABRA1
SCHEMBL29454364 0.85 MYC (0.41) KMT2AMAPTMEN1TDP1TSHR
SCHEMBL2505547 0.85 LMNA (0.42) KMT2AMAPTMEN1TDP1GABRA1
SCHEMBL29758267 0.85 KMT2A (0.41) KMT2AMAPTMEN1TDP1TSHR
SCHEMBL23121721 0.85 KMT2A (0.41) KMT2AMAPTMEN1TDP1TSHR
SCHEMBL2482061 0.85 PDE4A (0.41) KMT2AMAPTMEN1TDP1GABRA1
SCHEMBL30034611 0.84 KMT2A (0.39) KMT2AMAPTMEN1TDP1LMNA
SCHEMBL23139817 0.84 KMT2A (0.39) KMT2AMAPTMEN1TDP1LMNA
SCHEMBL2508117 0.83 KMT2A (0.41) KMT2AMAPTMEN1TDP1GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11993672-B2 Production of high melt flow propylene-based polymer and product from same W.R. GRACE & CO.-CONN. (US) 2024-05-28 US disclosed
US-20220177611-A1 PRODUCTION OF HIGH MELT FLOW PROPYLENE-BASED POLYMER AND PRODUCT FROM SAME W.R. GRACE & CO.-CONN. (US) 2022-06-09 US disclosed
US-20220177611-A1 PRODUCTION OF HIGH MELT FLOW PROPYLENE-BASED POLYMER AND PRODUCT FROM SAME W.R. GRACE & CO.-CONN. (US) 2022-06-09 US disclosed
US-11254756-B2 Process for production of high melt flow propylene-based polymer and product from same W.R. GRACE & CO.-CONN. (US) 2022-02-22 US disclosed
US-11254756-B2 Process for production of high melt flow propylene-based polymer and product from same W.R. GRACE & CO.-CONN. (US) 2022-02-22 US disclosed
EP-3074435-B1 PROCATALYST PARTICLES AND POLYMERIZATION PROCESS FOR IMPACT COPOLYMERS GRACE W R & CO (US) 2021-11-10 EP disclosed
US-20190338054-A1 Process For Production of High Melt Flow Propylene-Based Polymer and Product From Same W. R. GRACE & CO.-CONN. 2019-11-07 US disclosed
US-10358505-B2 Process for production of high melt flow propylene-based polymer and product from same W. R. GRACE & CO.-CONN. (US) 2019-07-23 US disclosed
US-10358505-B2 Process for production of high melt flow propylene-based polymer and product from same W. R. GRACE & CO.-CONN. (US) 2019-07-23 US disclosed
US-20180305479-A1 Procatalyst Particles And Polymerization Process For Impact Copolymers W. R. GRACE & CO.-CONN. (US) 2018-10-25 US disclosed
US-8604235-B2 Production of substituted phenylene aromatic diesters and compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2013-12-10 US disclosed
EP-2655313-A1 PROCESS FOR PRODUCTION OF HIGH MELT FLOW PROPYLENE-BASED POLYMER AND PRODUCT FROM SAME Dow Global Technologies LLC (US) 2013-10-30 EP disclosed
US-20130261273-A1 Process for Production of High Melt Flow Propylene-Based Polymer and Product from Same W. R. GRACE & CO.-CONN. 2013-10-03 US disclosed
US-20130261273-A1 Process for Production of High Melt Flow Propylene-Based Polymer and Product from Same W. R. GRACE & CO.-CONN. 2013-10-03 US disclosed
US-20130261273-A1 Process for Production of High Melt Flow Propylene-Based Polymer and Product from Same W. R. GRACE & CO.-CONN. 2013-10-03 US disclosed
WO-2012088028-A1 PROCESS FOR PRODUCTION OF HIGH MELT FLOW PROPYLENE-BASED POLYMER AND PRODUCT FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 WO disclosed
WO-2012088028-A1 PROCESS FOR PRODUCTION OF HIGH MELT FLOW PROPYLENE-BASED POLYMER AND PRODUCT FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 WO disclosed
EP-2376423-A1 PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS Dow Global Technologies LLC (US) 2011-10-19 EP disclosed
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions W. R. GRACE & CO.-CONN. 2010-08-12 US disclosed
WO-2010078519-A1 PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS DOW GLOBAL TECHNOLOGIES INC. (US) 2010-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100204506-A1 Production of Substituted Phenylene Aromatic Diesters and Compositions PAH, DDC, DDT KMT2A 1611/4885MAPT 2384/4885MEN1 3036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.