Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21142831 | 0.97 | L3MBTL1 (0.47) | L3MBTL1PLA2G2CMEN1KMT2ATDP1 | |
| SCHEMBL22507715 | 0.97 | L3MBTL1 (0.47) | L3MBTL1PLA2G2CMEN1KMT2ATDP1 | |
| SCHEMBL23081196 | 0.86 | HTT (0.55) | MEN1KMT2ACTSK | |
| SCHEMBL23081075 | 0.86 | PLA2G2C (0.43) | PLA2G2CMEN1KMT2ATDP1 | |
| SCHEMBL26016842 | 0.85 | KDM4E (0.43) | PLA2G2CMEN1KMT2ATDP1 | |
| SCHEMBL25106800 | 0.77 | PLA2G2C (0.38) | PLA2G2CMEN1KMT2AFAAHGPR84 | |
| SCHEMBL6125243 | 0.74 | KDM4E (0.42) | MEN1KMT2ATDP1CA1 | |
| SCHEMBL22790535 | 0.74 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ATDP1GPR84 | |
| SCHEMBL16664155 | 0.74 | CA1 (0.50) | L3MBTL1MEN1KMT2ATDP1GPR84 | |
| SCHEMBL23879488 | 0.74 | L3MBTL1 (0.47) | L3MBTL1MEN1KMT2ATDP1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230076435-A1 | MODIFIER OF FOUR-MEMBERED RING DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230076435-A1 | MODIFIER OF FOUR-MEMBERED RING DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | GRM4, GRM5, GRIA4 | L3MBTL1 4843/4885PLA2G2C 1604/4885MEN1 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.