Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 9/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 11/20 | 0.40 |
| ▸ | CDK2 | P24941 | 11/20 | 0.40 |
| ▸ | GSK3B | P49841 | 7/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23331071 | 0.75 | CCNE1 (0.42) | DRD3DRD2CCNE1CDK2GSK3B | |
| SCHEMBL24689836 | 0.73 | CCNE1 (0.41) | DRD3DRD2CCNE1CDK2GSK3B | |
| SCHEMBL24848501 | 0.71 | VHL (0.48) | CCNE1CDK2GSK3B | |
| SCHEMBL18606443 | 0.69 | CCNE2 (0.41) | CCNE1CDK2 | |
| SCHEMBL22015494 | 0.69 | CCNE1 (0.44) | CCNE1CDK2GSK3B | |
| SCHEMBL12307578 | 0.68 | CCNE1 (0.42) | CCNE1CDK2GSK3B | |
| SCHEMBL14631213 | 0.68 | ALDH1A1 (0.33) | — | |
| SCHEMBL22723848 | 0.68 | CCNE1 (0.40) | CCNE1CDK2GSK3B | |
| SCHEMBL28469752 | 0.68 | CCNE1 (0.40) | CCNE1CDK2 | |
| SCHEMBL12746893 | 0.67 | SMN1; SMN2 (0.54) | CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230076435-A1 | MODIFIER OF FOUR-MEMBERED RING DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230076435-A1 | MODIFIER OF FOUR-MEMBERED RING DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | GRM4, GRM5, GRIA4 | DRD3 367/4885DRD2 343/4885CCNE1 3938/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.