Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.47 |
| ▸ | CDK2 | P24941 | 10/20 | 0.47 |
| ▸ | GSK3B | P49841 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23331071 | 0.81 | CCNE1 (0.42) | CCNE1CDK2GSK3BCCNE2CDK4 | |
| SCHEMBL24689836 | 0.80 | CCNE1 (0.41) | CCNE1CDK2GSK3BCCNE2CDK4 | |
| SCHEMBL22015494 | 0.75 | CCNE1 (0.44) | CCNE1CDK2GSK3BCCNE2CDK4 | |
| SCHEMBL12307578 | 0.75 | CCNE1 (0.42) | CCNE1CDK2GSK3BLMNACCNE2 | |
| SCHEMBL22723848 | 0.74 | CCNE1 (0.40) | CCNE1CDK2GSK3BL3MBTL1CCNE2 | |
| Potassium Ion SCHEMBL22711543 | 0.73 | CCNE1 (0.40) | CCNE1CDK2GSK3BCCNE2CDK4 | |
| SCHEMBL25106914 | 0.71 | DRD3 (0.43) | CCNE1CDK2GSK3B | |
| SCHEMBL26336527 | 0.70 | VHL (0.54) | VHLL3MBTL1ALDH1A1MAPT | |
| SCHEMBL26339098 | 0.70 | VHL (0.50) | VHLLMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL22917314 | 0.69 | VHL (0.42) | VHLLMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230002364-A1 | BENZOTHIOPHENE DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002364-A1 | BENZOTHIOPHENE DERIVATIVE REGULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF | GPER1, GABRQ, GPR39 | VHL 2720/4885CCNE1 3184/4885CDK2 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.