Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25111293 | 0.90 | HRH3 (0.37) | HRH3RORC | |
| SCHEMBL25481249 | 0.83 | HRH3 (0.39) | HRH3RORC | |
| SCHEMBL25468369 | 0.82 | HRH3 (0.46) | HRH3RORC | |
| SCHEMBL25468377 | 0.81 | HRH3 (0.45) | HRH3RORC | |
| SCHEMBL25111055 | 0.80 | L3MBTL1 (0.33) | HRH3 | |
| SCHEMBL25111081 | 0.78 | HRH3 (0.39) | HRH3RORC | |
| SCHEMBL25481143 | 0.78 | RORC (0.36) | HRH3RORC | |
| SCHEMBL25109781 | 0.78 | HRH3 (0.48) | HRH3RORC | |
| SCHEMBL25109774 | 0.78 | HRH3 (0.56) | HRH3 | |
| SCHEMBL25108392 | 0.77 | RORC (0.39) | HRH3RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230072658-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230072658-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCB1, SMARCE1 | HRH3 1490/4885RORC 2353/4885ACHE 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.