Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CRYAB | P02511 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CRYAA | P02489 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 2/20 | 0.45 |
| ▸ | FNTB | P49356 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Obtusifoliol SCHEMBL13324285 | 1.00 | PTPN1 (0.50) | PTPN1CRYABMAPTUSP2ALDH1A1 | |
| Obtusifoliol SCHEMBL569375 | 1.00 | PTPN1 (0.50) | PTPN1CRYABMAPTUSP2ALDH1A1 | |
| Obtusifoliol SCHEMBL19270848 | 1.00 | PTPN1 (0.50) | PTPN1CRYABMAPTUSP2ALDH1A1 | |
| Obtusifoliol SCHEMBL8995509 | 1.00 | PTPN1 (0.50) | PTPN1CRYABMAPTUSP2ALDH1A1 | |
| Obtusifoliol SCHEMBL5489603 | 1.00 | PTPN1 (0.50) | PTPN1CRYABMAPTUSP2ALDH1A1 | |
| SCHEMBL2508949 | 0.86 | CRYAB (0.47) | PTPN1CRYABMAPTUSP2ALDH1A1 | |
| SCHEMBL29940774 | 0.83 | MAPT (0.68) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| SCHEMBL26641924 | 0.83 | MAPT (0.68) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| SCHEMBL26641929 | 0.83 | MAPT (0.68) | CRYABMAPTUSP2ALDH1A1CYP3A4 | |
| SCHEMBL25765071 | 0.82 | PTPN1 (0.37) | PTPN1CRYABMAPTUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118634309-B | Spleen-regulating and fat-reducing composition, and preparation method and application thereof | 云南中医药大学 | 2024-10-11 | — | — | CN | disclosed |
| CN-118634309-A | Spleen-regulating and fat-reducing composition, and preparation method and application thereof | 云南中医药大学 | 2024-09-13 | — | — | CN | disclosed |
| US-20140309186-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION | 2014-10-16 | — | — | US | disclosed |
| US-20110246081-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
| WO-2009052186-A1 | METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-04-23 | — | — | WO | disclosed |