Obtusifoliol

Obtusifoliol

SCHEMBL569375

C=C(CC[C@@H](C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)[C@@H](C)C1CC3)C(C)C

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.50
CRYAB P02511 5/20 0.47
MAPT P10636 3/20 0.47
USP2 O75604 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 2/20 0.47
ALOX15 P16050 2/20 0.47
LMNA P02545 1/20 0.47
CRYAA P02489 1/20 0.46
FNTA P49354 2/20 0.45
FNTB P49356 2/20 0.45
NR1I2 O75469 1/20 0.45
MEN1 O00255 1/20 0.43
PLA2G1B P04054 1/20 0.43
DNMT1 P26358 1/20 0.43
BLM P54132 1/20 0.43
KMT2A Q03164 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Obtusifoliol SCHEMBL13324285 1.00 PTPN1 (0.50) PTPN1CRYABMAPTUSP2ALDH1A1
Obtusifoliol SCHEMBL19270848 1.00 PTPN1 (0.50) PTPN1CRYABMAPTUSP2ALDH1A1
Obtusifoliol SCHEMBL8995509 1.00 PTPN1 (0.50) PTPN1CRYABMAPTUSP2ALDH1A1
Obtusifoliol SCHEMBL2511101 1.00 PTPN1 (0.50) PTPN1CRYABMAPTUSP2ALDH1A1
Obtusifoliol SCHEMBL5489603 1.00 PTPN1 (0.50) PTPN1CRYABMAPTUSP2ALDH1A1
SCHEMBL2508949 0.86 CRYAB (0.47) PTPN1CRYABMAPTUSP2ALDH1A1
SCHEMBL29940774 0.83 MAPT (0.68) CRYABMAPTUSP2ALDH1A1CYP3A4
SCHEMBL26641924 0.83 MAPT (0.68) CRYABMAPTUSP2ALDH1A1CYP3A4
SCHEMBL26641929 0.83 MAPT (0.68) CRYABMAPTUSP2ALDH1A1CYP3A4
SCHEMBL25765071 0.82 PTPN1 (0.37) PTPN1CRYABMAPTUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260020564-A1 FUNGAL DISEASES REDUCTION AND YIELD IMPROVEMENT METHODS AND COMPOSITION THEREOF ELICIT PLANT (FR) 2026-01-22 US claimed
US-20260020568-A1 FUNGAL DISEASES REDUCTION AND YIELD IMPROVEMENT METHODS AND COMPOSITION THEREOF ELICIT PLANT (FR) 2026-01-22 US claimed
CN-114306547-A Traditional Chinese medicine formula for regulating and controlling intestinal function of pregnant women 华子昂 2022-04-12 CN claimed
CN-102885937-A Preparation method and application of morelberry effective fractions JINAN XINGYI MED TECH CO LTD 2013-01-23 CN claimed
US-7906710-B2 Transgenic plants containing altered levels of steroid compounds MONSANTO COMPANY (US) 2011-03-15 US claimed
US-20100037354-A1 TRANSGENIC PLANTS CONTAINING ALTERED LEVELS OF STEROID COMPOUNDS KARUNANANDAA BALASULOJINI 2010-02-11 US claimed
EP-1301460-B9 METHOD FOR PREPARING A FATTY SUBSTANCE ESTER AND USE THEREOF IN PHARMACEUTICS, COSMETICS OR FOOD INDUSTRY EXPANSCIENCE LAB (FR) 2009-03-11 EP claimed
EP-1301460-B1 METHOD FOR PREPARING A FATTY SUBSTANCE ESTER AND USE THEREOF IN PHARMACEUTICS, COSMETICS OR FOOD INDUSTRY EXPANSCIENCE LAB (FR) 2008-08-06 EP claimed
CN-1227212-C Method for preparing aliphatic ester and application of aliphatic ester in pharmaceutical, cosmetic or food industry LAB PHARMASCIENCE (FR) 2005-11-16 CN claimed
US-20050086713-A1 Transgenic plants containing altered levels of steroid compounds KARUNANANDAA BALASULOJINI (US) 2005-04-21 US claimed
US-20040259732-A1 Treatment of plants and plant propagation materials with an antioxidant to improve plant health and/or yield MONSANTO TECHNOLOGY, L.L.C. 2004-12-23 US claimed
US-6828451-B2 Fatty substance is esterified with alcohol selected from sterols, stanols, 4-methylsterols and their hydrogenated homologs, triterpene alcohols, and mixtures, in presence of solid lanthanide metal oxide catalyst LABORATOIRES EXPANSCIENCE (FR) 2004-12-07 US claimed
WO-2004095926-A2 TREATMENT OF PLANTS AND PLANT PROPAGATION MATERIALS WITH AN ANTIOXIDANT TO IMPROVE PLANT HEALTH AND/OR YIELD MONSANTO TECHNOLOGY, LLC (US) 2004-11-11 WO claimed
EP-1381267-A2 TRANSGENIC PLANTS CONTAINING ALTERED LEVELS OF STEROID COMPOUNDS Monsanto Technology LLC (US) 2004-01-21 EP claimed
US-20030217384-A1 Obtusifoliol 14a-demethylase E. I. DU PONT DE NEMOURS AND COMPANY 2003-11-20 US claimed
US-20030195367-A1 Method for preparing a fatty substance ester and use thereof in pharmaceutics, cosmetics or food industry LABORATOIRES EXPANSCIENCE (FR) 2003-10-16 US claimed
US-20030150008-A1 Transgenic plants containing altered levels of steroid compounds MONSANTO TECHNOLOGY, L.L.C. 2003-08-07 US claimed
WO-2002061072-A2 TRANSGENIC PLANTS CONTAINING ALTERED LEVELS OF STEROID COMPOUNDS MONSANTO TECHNOLOGY LLC (US) 2002-08-08 WO claimed
US-12577526-B2 Massively parallel on-chip construction of synthetic microbial communities THE BROAD INSTITUTE, INC. (US) 2026-03-17 US disclosed
US-4808574-A LEUKOANTHOCYANES NAUCHNO-ISSLEDOVATELSKY INSTITUT SADOVODSTVA (SU) 1989-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195367-A1 Method for preparing a fatty substance ester and use thereof in pharmaceutics, cosmetics or food industry LSS, CYP51A1, CYP46A1 PTPN1 2796/4885CRYAB 4823/4885MAPT 4447/4885
US-20030150008-A1 Transgenic plants containing altered levels of steroid compounds HMGCR, CYP11A1, CYP46A1 PTPN1 4142/4885CRYAB 694/4885MAPT 3405/4885
US-20260020564-A1 FUNGAL DISEASES REDUCTION AND YIELD IMPROVEMENT METHODS AND COMPOSITION THEREOF FBP1, ERG28, CYP51A1 PTPN1 1161/4885CRYAB 3749/4885MAPT 1369/4885
US-20260020568-A1 FUNGAL DISEASES REDUCTION AND YIELD IMPROVEMENT METHODS AND COMPOSITION THEREOF GYS2, GYS1, FAR1 PTPN1 1198/4885CRYAB 4152/4885MAPT 3328/4885
US-12577526-B2 Massively parallel on-chip construction of synthetic microbial communities STUB1, SAMM50, CD14 PTPN1 85/4885CRYAB 1546/4885MAPT 1771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.