Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 5/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.70 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22783569 | 0.94 | CYP2C19 (0.71) | CYP2C19CYP2C9CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL22783563 | 0.94 | CYP2C9 (0.64) | CYP2C19CYP2C9CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL22783573 | 0.93 | CYP2C19 (0.70) | CYP2C19CYP2C9CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL22783687 | 0.92 | CYP2C19 (0.74) | CYP2C19CYP2C9CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL22783558 | 0.91 | CYP3A4 (0.61) | CYP2C19CYP2C9CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL2629210 | 0.89 | CYP2C19 (0.80) | CYP2C19CYP2C9CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL25113015 | 0.88 | CYP3A4 (0.55) | CYP2C19CYP2C9CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL2629209 | 0.87 | CYP2C19 (0.81) | CYP2C19CYP2C9CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL25113001 | 0.87 | CYP2C19 (0.75) | CYP2C19CYP2C9CYP2D6CYP3A4CYP1A2 | |
| SCHEMBL22783515 | 0.87 | CYP2C19 (0.75) | CYP2C19CYP2C9CYP2D6CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230079107-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS | CIDARA THERAPEUTICS, INC. | 2023-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230079107-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS | FCGR3B, FCGR1A, FCGR2A | CYP2C19 917/4885CYP2C9 1646/4885CYP2D6 1815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.