Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25112472 | 1.00 | LMNA (0.35) | LMNAHTTNR1I2PGRCYP3A4 | |
| SCHEMBL24096386 | 0.84 | PDE4B (0.37) | CYP2C9CYP2C19KDM4ESMN1; SMN2 | |
| SCHEMBL30362860 | 0.84 | PDE4B (0.37) | CYP2C9CYP2C19KDM4ESMN1; SMN2 | |
| SCHEMBL29154691 | 0.81 | CNKSR1 (0.43) | LMNAHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30739070 | 0.81 | CNKSR1 (0.43) | LMNAHTTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29154708 | 0.79 | L3MBTL1 (0.45) | LMNAKDM4EMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL27186830 | 0.79 | L3MBTL1 (0.45) | LMNAKDM4EMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL25743158 | 0.71 | CA12 (0.45) | LMNACYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL24096383 | 0.67 | LMNA (0.40) | LMNAHTTCYP3A4CYP2C19KDM4E | |
| SCHEMBL29698777 | 0.67 | LMNA (0.40) | LMNAHTTCYP3A4CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4148056-A1 | SOS1 INHIBITOR CONTAINING PHOSPHORUS | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-03-15 | — | — | EP | disclosed |