Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3554509 | 0.83 | ACE (0.30) | ACE | |
| SCHEMBL2924489 | 0.80 | ACE (0.32) | ACE | |
| SCHEMBL2091418 | 0.71 | — | — | |
| SCHEMBL13167831 | 0.71 | — | — | |
| SCHEMBL9409947 | 0.70 | ACE (0.54) | ACEALDH1A1KMT2A | |
| SCHEMBL1652402 | 0.70 | ACE (0.54) | ACEALDH1A1KMT2A | |
| SCHEMBL19253042 | 0.70 | ACE (0.54) | ACEALDH1A1KMT2A | |
| SCHEMBL6482583 | 0.68 | ACE (0.57) | ACEALDH1A1KMT2A | |
| SCHEMBL5778845 | 0.68 | ACE (0.57) | ACEALDH1A1KMT2A | |
| SCHEMBL1444662 | 0.68 | ACE (0.57) | ACEALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034388-B2 | Plant extract as anticancer agents | THE UNIVERSITY OF MARYLAND (US) | 2011-10-11 | — | — | US | disclosed |
| US-7812014-B2 | Bicyclic 6-alkylidene-penems as β-lactamase inhibitors | WYETH LLC (US) | 2010-10-12 | — | — | US | disclosed |
| US-7812014-B2 | Bicyclic 6-alkylidene-penems as β-lactamase inhibitors | WYETH LLC (US) | 2010-10-12 | — | — | US | disclosed |
| US-20080312203-A1 | Bicyclic 6-Alkylidene-Penems as Beta-Lactamase Inhibitors | WYETH (US) | 2008-12-18 | — | — | US | disclosed |
| US-20080312203-A1 | Bicyclic 6-Alkylidene-Penems as Beta-Lactamase Inhibitors | WYETH (US) | 2008-12-18 | — | — | US | disclosed |
| EP-1988093-A1 | Bicyclic 6-alkylidene-penems as beta-lactamases inhibitors | Wyeth a Corporation of the State of Delaware (US) | 2008-11-05 | — | — | EP | disclosed |
| US-20060159781-A1 | Anthocyanin-rich compositions and methods for inhibiting cancer cell growth | MAGNUSON BERNADENE A | 2006-07-20 | — | — | US | disclosed |
| US-20050013880-A1 | Anthocyanin-rich compositions and methods for inhibiting cancer cell growth | UNIVERSITY OF MARYLAND, THE | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060159781-A1 | Anthocyanin-rich compositions and methods for inhibiting cancer cell growth | MKI67, CCNC, CCNI | ACE 4092/4885ALDH1A1 1437/4885KMT2A 1538/4885 |
| US-20050013880-A1 | Anthocyanin-rich compositions and methods for inhibiting cancer cell growth | MKI67, CCNC, CCNI | ACE 4092/4885ALDH1A1 1437/4885KMT2A 1538/4885 |
| US-20080312203-A1 | Bicyclic 6-Alkylidene-Penems as Beta-Lactamase Inhibitors | PGLS, PEPD, B2M | ACE 168/4885ALDH1A1 1105/4885KMT2A 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.