Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25122374 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPK1L3MBTL1CYP2C19CYP1A2 | |
| SCHEMBL21397345 | 0.82 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1CYP2C19CYP1A2 | |
| SCHEMBL23054258 | 0.82 | S1PR5 (0.57) | ALDH1A1MAPK1L3MBTL1CYP2C19CYP1A2 | |
| SCHEMBL19966271 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1CYP2C19CYP1A2 | |
| SCHEMBL19465293 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1MAPK1L3MBTL1CYP2C19CYP1A2 | |
| SCHEMBL18909590 | 0.79 | SMN1; SMN2 (0.48) | ALDH1A1MAPK1L3MBTL1CYP2C19CYP1A2 | |
| SCHEMBL10859364 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1CYP2C19CYP1A2 | |
| SCHEMBL24970558 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1CYP2C19CYP1A2 | |
| SCHEMBL19604406 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1CYP2C19CYP1A2 | |
| SCHEMBL19934909 | 0.78 | FUCA1 (0.55) | ALDH1A1MAPK1L3MBTL1CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49481-E1 | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-04-04 | — | — | US | disclosed |