Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PRKX | P51817 | 1/20 | 0.49 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23734315 | 0.88 | ALDH1A1 (0.50) | S1PR5S1PR1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19465324 | 0.86 | NPC1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL19966271 | 0.86 | ALDH1A1 (0.53) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL19557165 | 0.86 | LTA4H (0.46) | S1PR5SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL20981267 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL10859364 | 0.84 | ALDH1A1 (0.61) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL19604406 | 0.84 | ALDH1A1 (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL24970558 | 0.84 | ALDH1A1 (0.50) | S1PR5SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL19934909 | 0.84 | FUCA1 (0.55) | SMN1; SMN2NPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL19778180 | 0.83 | HPGD (0.44) | S1PR5SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | Asteroid Therapeutics | 2023-10-26 | — | — | US | disclosed |
| US-20210060168-A1 | ASIALOGLYCOPROTEIN RECEPTOR MEDIATED DELIVERY OF THERAPEUTICALLY ACTIVE CONJUGATES | ARCTURUS THERAPEUTICS, INC. | 2021-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230340011-A1 | STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS | SREBF1, SREBF2, NR1H3 | S1PR5 372/4885S1PR1 302/4885SMN1; SMN2 4785/4885 |
| US-20210060168-A1 | ASIALOGLYCOPROTEIN RECEPTOR MEDIATED DELIVERY OF THERAPEUTICALLY ACTIVE CONJUGATES | ASGR1, FCGR2A, FCGR3B | S1PR5 323/4885S1PR1 198/4885SMN1; SMN2 3266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.