Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21646380 | 0.81 | MAP4K4 (0.42) | MAP4K4PIK3CDTGFBR1NTRK1EGFR | |
| SCHEMBL27154054 | 0.78 | ERBB2 (0.51) | ERBB2EGFR | |
| SCHEMBL25124483 | 0.77 | EGLN2 (0.45) | MAP4K4PIK3CDERBB2TGFBR1NTRK1 | |
| SCHEMBL21646347 | 0.75 | MAP4K4 (0.44) | MAP4K4PIK3CDTGFBR1AXLTDP1 | |
| SCHEMBL902674 | 0.74 | TGFBR1 (0.37) | MAP4K4PIK3CDTGFBR1NTRK1MAPK1 | |
| SCHEMBL22122747 | 0.72 | AURKB (0.38) | PIK3CDNTRK1EGFRKDRFLT1 | |
| SCHEMBL23691885 | 0.72 | TGFBR1 (0.34) | MAP4K4PIK3CDTGFBR1NTRK1MAPK1 | |
| SCHEMBL23055259 | 0.71 | IRAK4 (0.43) | MAP4K4PIK3CDNTRK1TDP1LMNA | |
| SCHEMBL23055242 | 0.71 | PIK3CD (0.38) | MAP4K4PIK3CDNTRK1TDP1EGFR | |
| SCHEMBL25335507 | 0.71 | MAPK1 (0.36) | MAP4K4PIK3CDTGFBR1NTRK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | Sumitomo Pharma Co., Ltd. (JP) | 2023-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230109839-A1 | THERAPEUTIC AGENT FOR TAUOPATHIES | MAPT, PSEN1, PSEN2 | MAP4K4 902/4885PIK3CD 3545/4885ERBB2 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.