Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 5/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511732 | 0.97 | SMPD1 (0.35) | SMPD1MAPTSMN1; SMN2 | |
| SCHEMBL2513085 | 0.96 | SMPD1 (0.37) | SMPD1TP53MAPTSMN1; SMN2F10 | |
| SCHEMBL2511923 | 0.93 | SCD (0.34) | SMPD1MAPTSMN1; SMN2SCD | |
| SCHEMBL2517583 | 0.93 | MAPT (0.38) | MAPTSMN1; SMN2 | |
| SCHEMBL2511915 | 0.89 | TLR7 (0.34) | PDE4DMAPTSMN1; SMN2 | |
| SCHEMBL627405 | 0.87 | SMPD1 (0.38) | SMPD1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2510945 | 0.84 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2 | |
| SCHEMBL627249 | 0.84 | MEN1 (0.37) | SMPD1MAPTSMN1; SMN2SCD | |
| SCHEMBL2515070 | 0.84 | KDM4E (0.36) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL2512730 | 0.84 | MAPT (0.33) | TP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592592-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | SMPD1 422/4885PDE4A 850/4885PDE4B 902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.