1,1-Dichloroethene

1,1-Dichloroethene

SCHEMBL251276

C=C(Cl)Cl.C=CCC(=O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.43
CYP2D6 P10635 2/20 0.43
ALDH1A1 P00352 1/20 0.43
ABCC4 O15439 1/20 0.36
MAPT P10636 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
BLM P54132 1/20 0.30
SLC6A3 Q01959 1/20 0.30
MEN1 O00255 1/20 0.30
NFKB1 P19838 1/20 0.30
CYP2C19 P33261 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,1-Dichloroethene SCHEMBL28116107 0.95 ALOX15 (0.39) ALOX15CYP2D6ALDH1A1ABCC4MAPT
Methacrylic Acid SCHEMBL8749282 0.89 ALOX15 (0.35) ALOX15CYP2D6ALDH1A1ABCC4MAPT
SCHEMBL23108 0.88
SCHEMBL10553508 0.88 ALDH1A1 (0.53) ALOX15CYP2D6ALDH1A1ABCC4MAPT
SCHEMBL9335555 0.88 ALDH1A1 (0.53) ALOX15CYP2D6ALDH1A1ABCC4MAPT
SCHEMBL10554896 0.88 ALDH1A1 (0.53) ALOX15CYP2D6ALDH1A1ABCC4MAPT
Hydrogen Peroxide SCHEMBL27498555 0.88
Vinyl Chloride SCHEMBL362756 0.86
Vinyl Chloride SCHEMBL10489200 0.86 ALOX15 (0.45) ALOX15CYP2D6ALDH1A1ABCC4MAPT
Vinyl Chloride SCHEMBL10858077 0.86 ALOX15 (0.45) ALOX15CYP2D6ALDH1A1ABCC4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2221663-B1 Reverse write erasable paper XEROX CORP (US) 2015-07-22 EP claimed
US-20150037732-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2015-02-05 US claimed
US-8603944-B2 Oligomeric spiropyrans for erasable medium applications XEROX CORPORATION (US) 2013-12-10 US claimed
US-8568952-B2 Method for manufacturing photoreceptor layers XEROX CORPORATION (US) 2013-10-29 US claimed
US-20130189616-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2013-07-25 US claimed
US-8211603-B2 Photoreceptor XEROX CORPORATION (US) 2012-07-03 US claimed
US-20120038718-A1 STABILIZED PHOTOCHROMIC INK FOR REUSABLE PAPER ANNOTATION XEROX CORPORATION (US) 2012-02-16 US claimed
US-7964271-B2 Photochromic medium with erase-on-demand capability XEROX CORPORATION (US) 2011-06-21 US claimed
US-20110092364-A1 OLIGOMERIC SPIROPYRANS FOR ERASABLE MEDIUM APPLICATIONS XEROX CORPORATION (US) 2011-04-21 US claimed
US-20110082035-A1 PHOTOCHROMIC MATERIALS INCORPORATED IN POLYMER BACKBONE XEROX CORPORATION (US) 2011-04-07 US claimed
US-20060210894-A1 Imaging members XEROX CORPORATION 2006-09-21 US claimed
US-20060099525-A1 Imaging member XEROX CORPORATION 2006-05-11 US claimed
US-20050233230-A1 Photosensitive member having anti-curl backing layer with lignin sulfonic acid doped polyaniline XEROX CORPORATION 2005-10-20 US claimed
US-6933089-B2 comprises dual charge transport layer comprising photogenerating layer, binder, and hindered phenol dopant; photoreceptors; improved electrical performance/print quality XEROX CORPORATION (US) 2005-08-23 US claimed
US-20040115545-A1 Imaging members XEROX CORPORATION 2004-06-17 US claimed
US-20040072088-A1 Flexible electrostatographic imaging member XEROX CORPORATION 2004-04-15 US claimed
EP-0539655-A2 Blends of comb-shaped copolymers of a macromolecular monomer of polylactone with polymer (s) THE B.F. GOODRICH COMPANY (US) 1993-05-05 EP claimed
US-5177151-A Adhesives, impact modifier, heat resistance THE B. F. GOODRICH COMPANY (US) 1993-01-05 US claimed
US-5156709-A Optically detectable stripe which becomes transparent on application of heat or pressure XEROX CORPORATION (US) 1992-10-20 US claimed
US-5120790-A Combatible THE B. F. GOODRICH COMPANY (US) 1992-06-09 US claimed