Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25128148 | 0.84 | PSMB5 (0.47) | PSMB5RENCTSDBACE1 | |
| SCHEMBL22851449 | 0.75 | PSMB5 (0.57) | PSMB5SMN1; SMN2TP53HPGDGAA | |
| SCHEMBL13154048 | 0.75 | CYP2C9 (0.43) | ALDH1A1TDP1KMT2ATSHR | |
| SCHEMBL6367910 | 0.75 | CYP2C9 (0.43) | ALDH1A1TDP1KMT2ATSHR | |
| SCHEMBL16587847 | 0.73 | NOD1 (0.38) | PSMB5 | |
| SCHEMBL23817738 | 0.73 | PSMB5 (0.54) | PSMB5SMN1; SMN2TP53HPGDGAA | |
| SCHEMBL23792690 | 0.72 | NOD1 (0.34) | CTSDALDH1A1TDP1KMT2ATSHR | |
| SCHEMBL8736851 | 0.71 | NOD1 (0.45) | PSMB5TDP1KMT2A | |
| SCHEMBL23289285 | 0.71 | PSMB5 (0.42) | PSMB5 | |
| SCHEMBL21074906 | 0.71 | PSMB5 (0.46) | PSMB5RENCTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023040793-A1 | ANTI-INFLAMMATORY COMPOUND AND USE THEREOF | 映恩生物制药（苏州）有限公司 | 2023-03-23 | — | — | WO | disclosed |