Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | BMP1 | P13497 | 2/20 | 0.38 |
| ▸ | GGH | Q92820 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26173989 | 0.88 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLABMP1GGH | |
| SCHEMBL25129090 | 0.86 | FOLH1 (0.40) | FOLH1NAALAD2RIMKLABMP1GGH | |
| SCHEMBL25128148 | 0.84 | PSMB5 (0.47) | PSMB5FOLH1NAALAD2RIMKLABMP1 | |
| SCHEMBL24622679 | 0.82 | FOLH1 (0.35) | PSMB5FOLH1NAALAD2RIMKLABMP1 | |
| SCHEMBL19681930 | 0.79 | BMP1 (0.39) | FOLH1NAALAD2RIMKLABMP1KEAP1 | |
| SCHEMBL23863721 | 0.78 | SIRT6 (0.45) | PSMB5FOLH1 | |
| SCHEMBL23289287 | 0.78 | SIRT6 (0.45) | PSMB5FOLH1 | |
| SCHEMBL15158367 | 0.78 | PSMB5 (0.45) | PSMB5 | |
| SCHEMBL12094213 | 0.78 | NOD1 (0.41) | FOLH1NOD1PLA2G2C | |
| SCHEMBL25128949 | 0.77 | FOLH1 (0.38) | PSMB5FOLH1NAALAD2RIMKLABMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289857-A1 | DRUG CONJUGATE OF GLUCOCORTICOID RECEPTOR AGONIST, AND APPLICATION THEREOF IN MEDICINE | Shanghai Senhui Medicine Co., Ltd. (CN) | 2023-12-13 | — | — | EP | disclosed |
| EP-3884962-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | AbbVie Inc. (US) | 2021-09-29 | — | — | EP | disclosed |
| EP-3658192-B1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | ABBVIE INC (US) | 2021-04-28 | — | — | EP | disclosed |