Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29142108 | 0.85 | DPP4 (0.68) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL21985108 | 0.85 | DPP4 (0.68) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL21985104 | 0.85 | DPP4 (0.68) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL25129574 | 0.76 | DPP4 (0.80) | DPP4DPP7DPP9 | |
| SCHEMBL4411399 | 0.74 | DPP4 (0.55) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL4550662 | 0.74 | DPP4 (0.55) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL24244598 | 0.73 | DPP4 (0.79) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL28434489 | 0.73 | DPP4 (0.79) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL21985113 | 0.72 | DPP4 (0.84) | DPP4CYP3A4DPP7DPP9 | |
| SCHEMBL21985114 | 0.72 | DPP4 (0.84) | DPP4CYP3A4DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230103175-A1 | TRANSAMINASE MUTANT, IMMOBILIZED TRANSAMINASE AND USE IN PREPARATION OF SITAGLIPTIN | ABIOCHEM BIOTECHNOLOGY CO, LTD. (CN) | 2023-03-30 | — | — | US | disclosed |