Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.68 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29142108 | 1.00 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL21985108 | 1.00 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL24244598 | 0.88 | DPP4 (0.79) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL28434489 | 0.88 | DPP4 (0.79) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL4411399 | 0.87 | DPP4 (0.55) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL4550662 | 0.87 | DPP4 (0.55) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL25840236 | 0.86 | DPP4 (0.77) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL4699518 | 0.85 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL4699986 | 0.85 | DPP4 (0.68) | DPP4DPP7CYP3A4DPP9 | |
| SCHEMBL25129752 | 0.85 | DPP4 (0.53) | DPP4DPP7CYP3A4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250313814-A1 | OMEGA-TRANSAMINASE MUTANT AND APPLICATION THEREOF | ZHEJIANG YONGTAI PHARMACEUTICAL CO., LTD. (CN) | 2025-10-09 | — | — | US | disclosed |
| EP-4506451-A1 | OMEGA-TRANSAMINASE MUTANT AND USE THEREOF | Zhejiang Yongtai Technology Co., Ltd. (CN) | 2025-02-12 | — | — | EP | disclosed |
| CN-113061594-B | Transaminase mutants, immobilized transaminases and use for preparing sitagliptin | 弈柯莱生物科技(集团)股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| WO-2022257686-A1 | TRANSAMINASE, IMMOBILIZED TRANSAMINASE AND USE FOR PREPARING SITAGLIPTIN | 弈柯莱生物科技(上海)股份有限公司 | 2022-12-15 | — | — | WO | disclosed |
| WO-2021135886-A1 | TRANSAMINASE MUTANT, IMMOBILIZED TRANSAMINASE AND USE IN PREPARATION OF SITAGLIPTIN | 弈柯莱生物科技(上海)股份有限公司 | 2021-07-08 | — | — | WO | disclosed |
| EP-3650537-A1 | USE OF STEREOSELECTIVE TRANSAMINASE IN ASYMMETRIC SYNTHESIS OF CHIRAL AMINE | Abiochem Biotechnology Co., Ltd. (CN) | 2020-05-13 | — | — | EP | disclosed |