Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016118 | 0.86 | P2RX3 (0.61) | P2RX3 | |
| SCHEMBL29016116 | 0.86 | P2RX3 (0.61) | P2RX3 | |
| SCHEMBL15038609 | 0.80 | P2RX3 (0.56) | P2RX3 | |
| SCHEMBL28675482 | 0.80 | P2RX3 (0.70) | P2RX3 | |
| SCHEMBL15215787 | 0.80 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL12045883 | 0.79 | P2RX3 (0.69) | P2RX3 | |
| SCHEMBL15081125 | 0.79 | P2RX3 (0.69) | P2RX3 | |
| SCHEMBL15180911 | 0.78 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL17590716 | 0.78 | P2RX3 (0.53) | P2RX3 | |
| SCHEMBL10056258 | 0.78 | P2RX3 (0.66) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240391904-A1 | DIHYDROPYRIMIDINE BASED COMPOUND, PREPARATION METHOD THEREFOR AND USE OF THEREOF | CHENGDU SHIBEIKANG BIOMEDICAL TECHNOLOGY CO., LTD. (CN) | 2024-11-28 | — | — | US | disclosed |
| EP-4410785-A1 | DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Chengdu Shibeikang Biomedical Technology Co., Ltd. (CN) | 2024-08-07 | — | — | EP | disclosed |
| CN-113620888-B | Dihydropyrimidine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-06-06 | — | — | CN | disclosed |
| WO-2023046133-A1 | DIHYDROPYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 成都施贝康生物医药科技有限公司 | 2023-03-30 | — | — | WO | disclosed |
| CN-113666914-B | Dihydropyrimidine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2022-06-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240391904-A1 | DIHYDROPYRIMIDINE BASED COMPOUND, PREPARATION METHOD THEREFOR AND USE OF THEREOF | P2RX3, P2RX6, P2RX7 | P2RX3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.