Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 17/20 | 0.78 |
| ▸ | GLA | P06280 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.77 |
| ▸ | RECQL | P46063 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | POLB | P06746 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.76 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.75 |
| ▸ | BLM | P54132 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27432679 | 0.92 | TOP1 (0.75) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL5323807 | 0.91 | TOP1 (0.81) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL22893112 | 0.90 | TOP1 (0.79) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL27432677 | 0.89 | TOP1 (0.77) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL7633084 | 0.89 | TOP1 (0.77) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL17077988 | 0.89 | TOP1 (0.78) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL8078009 | 0.89 | TOP1 (0.81) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL7629235 | 0.89 | TOP1 (0.84) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL7631826 | 0.88 | TOP1 (0.83) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL7626877 | 0.88 | TOP1 (0.81) | TOP1GLASMN1; SMN2ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2023-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230115871-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | CD2BP2, EPCAM, CD74 | TOP1 174/4885GLA 2807/4885SMN1; SMN2 2840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.