Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 17/20 | 0.79 |
| ▸ | GLA | P06280 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | RECQL | P46063 | 2/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.77 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.77 |
| ▸ | NPC1 | O15118 | 1/20 | 0.77 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323807 | 0.92 | TOP1 (0.81) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL17077988 | 0.90 | TOP1 (0.78) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL25130174 | 0.90 | TOP1 (0.78) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL27434176 | 0.89 | TOP1 (0.81) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL7631826 | 0.89 | TOP1 (0.83) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL7626877 | 0.89 | TOP1 (0.81) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL1006662 | 0.88 | TOP1 (1.00) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL27561956 | 0.88 | TOP1 (1.00) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL17897687 | 0.88 | TOP1 (0.82) | TOP1GLASMN1; SMN2ALDH1A1RECQL | |
| SCHEMBL18310362 | 0.88 | TOP1 (1.00) | TOP1GLASMN1; SMN2ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634508-B2 | Peptide conjugates of cytotoxins as therapeutics | Cybrexa 2, Inc. (US) | 2023-04-25 | — | — | US | disclosed |
| US-20210009719-A1 | PEPTIDE CONJUGATES OF CYTOTOXINS AS THERAPEUTICS | Cybrexa 2, Inc. | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634508-B2 | Peptide conjugates of cytotoxins as therapeutics | TOP1, TOP2A, TOP2B | TOP1 1/4885GLA 2632/4885SMN1; SMN2 3041/4885 |
| US-20210009719-A1 | PEPTIDE CONJUGATES OF CYTOTOXINS AS THERAPEUTICS | TOP1, TOP2A, TOP2B | TOP1 1/4885GLA 2632/4885SMN1; SMN2 3041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.