Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.46 |
| ▸ | TSHR | P16473 | 8/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25131153 | 0.87 | APLNR (0.54) | APLNRKDM4CCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30205616 | 0.87 | APLNR (0.54) | APLNRKDM4CCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25131339 | 0.86 | APLNR (0.52) | APLNRKDM4CCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25131733 | 0.85 | APLNR (0.51) | APLNRKDM4CCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29284223 | 0.84 | APLNR (0.50) | APLNRKDM4CCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29552308 | 0.83 | KDM4C (0.58) | APLNRKDM4CCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29922728 | 0.83 | KDM4C (0.53) | APLNRKDM4CCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27007123 | 0.83 | KDM4C (0.53) | APLNRKDM4CCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25131014 | 0.83 | APLNR (0.49) | APLNRKDM4CCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30226787 | 0.83 | APLNR (0.49) | APLNRKDM4CCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023046698-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-03-30 | — | — | WO | disclosed |