Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27007123 | 1.00 | KDM4C (0.53) | KDM4CMAPTAPLNRALDH1A1TSHR | |
| SCHEMBL29552308 | 0.91 | KDM4C (0.58) | KDM4CMAPTAPLNRALDH1A1TSHR | |
| SCHEMBL29937050 | 0.90 | KDM4C (0.52) | KDM4CMAPTAPLNRALDH1A1TSHR | |
| SCHEMBL2135922 | 0.88 | KDM4C (0.52) | KDM4CMAPTAPLNRALDH1A1TSHR | |
| SCHEMBL2599620 | 0.84 | KDM4C (0.50) | KDM4CMAPTAPLNRALDH1A1TSHR | |
| SCHEMBL23015337 | 0.83 | KDM4E (0.48) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL25130656 | 0.83 | APLNR (0.51) | KDM4CMAPTAPLNRALDH1A1TSHR | |
| SCHEMBL25131153 | 0.83 | APLNR (0.54) | KDM4CAPLNRALDH1A1TSHRERBB2 | |
| SCHEMBL30205616 | 0.83 | APLNR (0.54) | KDM4CAPLNRALDH1A1TSHRERBB2 | |
| SCHEMBL23486593 | 0.83 | KDM4C (0.56) | KDM4CMAPTAPLNRALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096719-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-110818641-B | Pyridazine-3-formamide compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-10-14 | — | — | CN | disclosed |