Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 3/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25132901 | 0.87 | ALB (0.37) | TSHRALDH1A1ALBCASP2NAAA | |
| SCHEMBL25132500 | 0.87 | ALB (0.37) | TSHRALDH1A1ALBCASP2NAAA | |
| SCHEMBL25132903 | 0.87 | ALB (0.37) | TSHRALDH1A1ALBCASP2NAAA | |
| SCHEMBL26773565 | 0.87 | NAMPT (0.41) | TSHRALDH1A1ALBCASP2NAAA | |
| SCHEMBL23664521 | 0.87 | CASP2 (0.47) | CASP2NAAANOD1FAAHCNR1 | |
| SCHEMBL25132935 | 0.86 | CASP2 (0.37) | TSHRALDH1A1ALBCASP2NAAA | |
| SCHEMBL13695157 | 0.84 | ALB (0.40) | TSHRALDH1A1ALBCASP2NAAA | |
| SCHEMBL23463505 | 0.84 | ALDH1A1 (0.38) | TSHRALDH1A1ALBCASP2NAAA | |
| SCHEMBL16843241 | 0.80 | CASP2 (0.44) | TSHRALDH1A1CASP2NAAALMNA | |
| SCHEMBL26700957 | 0.79 | NAMPT (0.45) | TSHRALDH1A1CASP2NAAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023057812-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDER | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |
| WO-2023057813-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |