Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20016488 | 0.89 | OPRK1 (0.33) | KDM4EALDH1A1ITGB3ITGA2B | |
| SCHEMBL17662433 | 0.86 | KDM4E (0.35) | KDM4EALDH1A1ITGB3ITGA2BNPSR1 | |
| SCHEMBL16248631 | 0.86 | KDM4E (0.35) | KDM4EALDH1A1ITGB3ITGA2BNPSR1 | |
| SCHEMBL11956479 | 0.86 | KDM4E (0.35) | KDM4EALDH1A1ITGB3ITGA2BNPSR1 | |
| SCHEMBL26231094 | 0.85 | KISS1R (0.41) | — | |
| SCHEMBL13468552 | 0.85 | KISS1R (0.41) | — | |
| SCHEMBL24703969 | 0.84 | KDM4E (0.34) | KDM4EALDH1A1ITGB3ITGA2B | |
| SCHEMBL24678191 | 0.84 | KDM4E (0.34) | KDM4EALDH1A1ITGB3ITGA2B | |
| SCHEMBL17642082 | 0.84 | KISS1R (0.36) | KDM4EALDH1A1ITGB3ITGA2BNPSR1 | |
| SCHEMBL15315080 | 0.84 | KISS1R (0.36) | KDM4EALDH1A1ITGB3ITGA2BNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023057813-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR THE TREATMENT, PREVENTION, OR MANAGEMENT OF HYPERPROLIFERATIVE DISORDERS | VINCERX PHARMA GMBH (DE) | 2023-04-13 | — | — | WO | disclosed |