Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | IDE | P14735 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 8/20 | 0.58 |
| ▸ | HLCS | P50747 | 5/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2514439 | 1.00 | TDP1 (0.67) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL9241448 | 0.93 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL6884034 | 0.91 | HLCS (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL8760672 | 0.90 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL9241912 | 0.90 | TDP1 (0.60) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL3120163 | 0.90 | TDP1 (0.54) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL8578177 | 0.90 | TDP1 (0.54) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL712974 | 0.88 | HLCS (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL6883588 | 0.88 | TDP1 (0.52) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL4295408 | 0.88 | TDP1 (0.52) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552202-A1 | METHODS AND COMPOSITIONS FOR WEIGHT LOSS | SDG, Inc. (US) | 2013-02-06 | — | — | EP | claimed |
| WO-2011119953-A1 | METHODS AND COMPOSITIONS FOR WEIGHT LOSS | SDG, INC. (US) | 2011-09-29 | — | — | WO | claimed |