Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | PDK2 | Q15119 | 9/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11469925 | 0.84 | THRB (1.00) | THRBTDP1PDK2CA1CA2 | |
| SCHEMBL30488775 | 0.84 | THRB (1.00) | THRBTDP1PDK2CA1CA2 | |
| SCHEMBL66735 | 0.84 | THRB (1.00) | THRBTDP1PDK2CA1CA2 | |
| Bromomethane SCHEMBL208217 | 0.82 | THRB (0.88) | THRBTDP1PDK2ALDH1A1HTT | |
| Bromide SCHEMBL27743796 | 0.82 | THRB (0.95) | THRBTDP1PDK2CA1CA2 | |
| SCHEMBL30519841 | 0.80 | THRB (0.70) | THRBTDP1PDK2 | |
| SCHEMBL68561 | 0.80 | THRB (0.70) | THRBTDP1PDK2 | |
| SCHEMBL10970276 | 0.80 | THRB (0.70) | THRBTDP1PDK2CA1CA2 | |
| Methyl Alcohol SCHEMBL21134117 | 0.80 | THRB (0.91) | THRBTDP1PDK2ALDH1A1HTT | |
| SCHEMBL28937357 | 0.77 | THRB (0.84) | THRBTDP1PDK2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023055702-A1 | MAIN PROTEASE (M PRO) INHIBITORS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-04-06 | — | — | WO | disclosed |