SCHEMBL25134396

SCHEMBL25134396

CCNC(=O)C(=O)[C@@H](C)C[C@@H]1CCNC1=O

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 1/20 0.35
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25134402 0.86 CTSL (0.36) CTSLCTSB
SCHEMBL25134405 0.86 CTSL (0.36) CTSLCTSB
SCHEMBL25134401 0.83 CTSL (0.44) CCR2CTSLCTSB
SCHEMBL25134399 0.83 CTSL (0.44) CCR2CTSLCTSB
SCHEMBL25134791 0.80 CTSL (0.35) CTSLCTSB
SCHEMBL25135053 0.80 CTSL (0.35) CTSLCTSB
SCHEMBL25761980 0.77 CAPN1 (0.36) CTSL
SCHEMBL30009270 0.77 CAPN1 (0.36) CTSL
SCHEMBL30913966 0.77 NOD1 (0.49) CCR2CTSLCTSB
SCHEMBL25761982 0.77 CTSL (0.39) CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023055702-A1 MAIN PROTEASE (M PRO) INHIBITORS AND METHODS USING SAME ARBUTUS BIOPHARMA CORPORATION (CA) 2023-04-06 WO disclosed