Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 14/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182239 | 1.00 | CD38 (0.46) | CD38CYP2D6CYP2B6CYP2C19WNT1 | |
| SCHEMBL30182602 | 1.00 | CD38 (0.46) | CD38CYP2D6CYP2B6CYP2C19WNT1 | |
| SCHEMBL29182229 | 0.91 | CD38 (0.46) | CD38CYP2D6CYP2B6CYP2C19WNT1 | |
| SCHEMBL25135976 | 0.91 | CD38 (0.46) | CD38CYP2D6CYP2B6CYP2C19WNT1 | |
| SCHEMBL30182904 | 0.91 | CD38 (0.46) | CD38CYP2D6CYP2B6CYP2C19WNT1 | |
| SCHEMBL30363822 | 0.87 | CD38 (0.49) | CD38CYP2D6CYP2B6CYP2C19WNT1 | |
| SCHEMBL29182179 | 0.87 | CD38 (0.49) | CD38CYP2D6CYP2B6CYP2C19WNT1 | |
| SCHEMBL25136495 | 0.87 | CD38 (0.49) | CD38CYP2D6CYP2B6CYP2C19WNT1 | |
| SCHEMBL25136199 | 0.86 | HPGDS (0.35) | CD38CYP2D6CYP2B6WNT1GSK3B | |
| SCHEMBL29182168 | 0.86 | HPGDS (0.35) | CD38CYP2D6CYP2B6WNT1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813296-A | CD38 modulators and methods of use thereof | 赛特凯恩蒂克公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CYTOKINETICS, INC. | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CD38, CXCR4, FCGRT | CD38 1/4885CYP2D6 1605/4885CYP2B6 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.