Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 11/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 2/20 | 0.33 |
| ▸ | RBP4 | P02753 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29182168 | 1.00 | HPGDS (0.35) | HPGDSCYP3A4CYP2D6IDO1CYP2B6 | |
| SCHEMBL30182872 | 1.00 | HPGDS (0.35) | HPGDSCYP3A4CYP2D6IDO1CYP2B6 | |
| SCHEMBL30182612 | 0.92 | RORC (0.37) | CYP3A4CYP2D6IDO1CYP2B6KCNH2 | |
| SCHEMBL29182202 | 0.92 | RORC (0.37) | CYP3A4CYP2D6IDO1CYP2B6KCNH2 | |
| SCHEMBL25135950 | 0.92 | RORC (0.37) | CYP3A4CYP2D6IDO1CYP2B6KCNH2 | |
| SCHEMBL25136188 | 0.88 | ALDH1A1 (0.40) | HPGDSCYP3A4CYP2D6IDO1CYP2B6 | |
| SCHEMBL25136297 | 0.88 | ALDH1A1 (0.40) | HPGDSCYP3A4CYP2D6IDO1CYP2B6 | |
| SCHEMBL29182201 | 0.88 | ALDH1A1 (0.40) | HPGDSCYP3A4CYP2D6IDO1CYP2B6 | |
| SCHEMBL25136255 | 0.86 | CD38 (0.46) | HPGDSCYP2D6CYP2B6CD38WNT1 | |
| SCHEMBL29182239 | 0.86 | CD38 (0.46) | HPGDSCYP2D6CYP2B6CD38WNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CYTOKINETICS, INC. | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CD38, CXCR4, FCGRT | HPGDS 1523/4885CYP3A4 538/4885CYP2D6 1605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.