SCHEMBL25138532

SCHEMBL25138532

CC(C)C(=O)OCC1(CO)C/C(=C\c2ccc3ccn(C)c3c2)C(=O)O1

nearest known ligand 0.81

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 7/20 0.81
RASGRP1 O95267 4/20 0.81
PRKCE Q02156 4/20 0.81
RASGRP3 Q8IV61 4/20 0.81
PRKCD Q05655 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25138629 0.93 PRKCA (0.81) PRKCARASGRP1PRKCERASGRP3PRKCD
SCHEMBL25138528 0.88 PRKCA (0.85) PRKCARASGRP1PRKCERASGRP3
SCHEMBL25138631 0.81 PRKCA (0.85) PRKCARASGRP1PRKCERASGRP3
SCHEMBL25138743 0.81 PRKCA (0.81) PRKCARASGRP1PRKCERASGRP3PRKCD
SCHEMBL25138527 0.81 PRKCA (0.81) PRKCARASGRP1PRKCERASGRP3PRKCD
SCHEMBL25138755 0.76 PRKCA (0.83) PRKCARASGRP1PRKCERASGRP3PRKCD
SCHEMBL25138526 0.70 PRKCA (0.84) PRKCARASGRP1PRKCERASGRP3PRKCD
SCHEMBL25138756 0.70 PRKCA (0.84) PRKCARASGRP1PRKCERASGRP3
SCHEMBL25138753 0.65 PRKCA (0.85) PRKCARASGRP1PRKCERASGRP3PRKCD
SCHEMBL2422125 0.60 PIM1 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230117831-A1 MULTI-FUNCTIONAL CHIMERIC MOLECULES THE BROAD INSTITUTE, INC. 2023-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230117831-A1 MULTI-FUNCTIONAL CHIMERIC MOLECULES PHAX, PAICS, SARS1 PRKCA 2333/4885RASGRP1 1904/4885PRKCE 2210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.