Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 13/20 | 0.84 |
| ▸ | RASGRP3 | Q8IV61 | 13/20 | 0.84 |
| ▸ | RASGRP1 | O95267 | 5/20 | 0.84 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25138743 | 0.88 | PRKCA (0.81) | PRKCARASGRP3RASGRP1PRKCE | |
| SCHEMBL25138526 | 0.87 | PRKCA (0.84) | PRKCARASGRP3RASGRP1PRKCE | |
| SCHEMBL25138631 | 0.83 | PRKCA (0.85) | PRKCARASGRP3RASGRP1PRKCE | |
| SCHEMBL25138528 | 0.83 | PRKCA (0.85) | PRKCARASGRP3RASGRP1PRKCE | |
| SCHEMBL25138753 | 0.81 | PRKCA (0.85) | PRKCARASGRP3RASGRP1PRKCE | |
| SCHEMBL25138527 | 0.74 | PRKCA (0.81) | PRKCARASGRP3RASGRP1PRKCE | |
| SCHEMBL25138629 | 0.70 | PRKCA (0.81) | PRKCARASGRP3RASGRP1PRKCE | |
| SCHEMBL25138532 | 0.70 | PRKCA (0.81) | PRKCARASGRP3RASGRP1PRKCE | |
| SCHEMBL25138755 | 0.67 | PRKCA (0.83) | PRKCARASGRP3RASGRP1PRKCE | |
| SCHEMBL8349589 | 0.59 | PRKCA (1.00) | PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117831-A1 | MULTI-FUNCTIONAL CHIMERIC MOLECULES | THE BROAD INSTITUTE, INC. | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117831-A1 | MULTI-FUNCTIONAL CHIMERIC MOLECULES | PHAX, PAICS, SARS1 | PRKCA 2333/4885RASGRP3 1973/4885RASGRP1 1904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.