Pyridine

Pyridine

SCHEMBL251401

Cc1ccccc1S(=O)(=O)O.c1ccncc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.47
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47
MYC P01106 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
NAPRT Q6XQN6 1/20 0.40
ALKBH2 Q6NS38 1/20 0.40
ALKBH3 Q96Q83 1/20 0.40
NAMPT P43490 3/20 0.39
TSHR P16473 1/20 0.39
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
RAPGEF4 Q8WZA2 1/20 0.38
KMT2A Q03164 1/20 0.38
TBXAS1 P24557 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28150876 0.98 TDP1 (0.46) TDP1ALDH1A1TP53MYCSMN1; SMN2
Pyridine SCHEMBL28284596 0.96 TDP1 (0.49) TDP1ALDH1A1TP53MYCSMN1; SMN2
Piperazine SCHEMBL28195269 0.91 ALDH1A1 (0.41) TDP1ALDH1A1TP53MYCSMN1; SMN2
Pyridine SCHEMBL28141506 0.91 TDP1 (0.41) TDP1ALDH1A1TP53MYCSMN1; SMN2
Methyl Alcohol SCHEMBL27773140 0.88 MYC (0.52) TDP1ALDH1A1TP53MYCSMN1; SMN2
Benzene SCHEMBL8718895 0.88 MYC (0.52) TDP1MYCSMN1; SMN2KDM4ELMNA
Pyridine SCHEMBL19742951 0.86 NAPRT (0.47) TDP1ALDH1A1MYCSMN1; SMN2KDM4E
Benzene SCHEMBL28093278 0.86 MYC (0.50) TDP1MYCSMN1; SMN2KDM4ELMNA
SCHEMBL1748 0.86 MYC (0.53) TDP1ALDH1A1TP53MYCSMN1; SMN2
SCHEMBL29392580 0.86 MYC (0.53) TDP1ALDH1A1TP53MYCSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 869 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024109742-A1 METHOD FOR EFFICIENTLY SYNTHESIZING BUFADIENOLIDES AND DERIVATIVES THEREOF 上海中医药大学 2024-05-30 WO claimed
CN-114991738-B Sandstone reservoir composite reconstruction method 中国石油天然气股份有限公司 2024-03-26 CN claimed
CN-116057065-A Process for the preparation of (3 alpha, 5 alpha) -3-hydroxy-3-methyl-pregnan-20-one (ganaxolone) 工业化学有限公司 2023-05-02 CN claimed
EP-3883913-A1 PROCESS FOR MAKING ETHERS VIA ENOL ETHERS BP P.L.C. (GB) 2021-09-29 EP claimed
CN-106565442-B The preparation method of 3- (3- luorobenzyl) -4- (3- fluorine benzyloxy) benzaldehyde 浙江美诺华药物化学有限公司 2019-07-16 CN claimed
CN-109021065-A A method of preparing high anti-cancer activity peptide aplysiatoxin Dolastatin10 复旦大学 2018-12-18 CN claimed
CN-108558820-A A kind of preparation method of acrylic -1,3- propane sultones 苏州华新能源科技有限公司 2018-09-21 CN claimed
CN-105733656-B FCC gasoline oxidation desulfurization method of composite acidic ionic liquid 中国石油天然气股份有限公司 2017-10-17 CN claimed
CN-105733656-A FCC gasoline oxidation desulfurization method of composite acidic ionic liquid 中国石油天然气股份有限公司 2016-07-06 CN claimed
CN-103804403-B A kind of method of preparing 2-hydroxy benzenes boric acid CHINA SYNCHEM TECHNOLOGY CO., LTD. (CN) 2016-05-18 CN claimed
WO-2005037821-A2 PREPARATION OF CANDESARTAN CILEXETIL TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2005-04-28 WO claimed
US-6025177-A ENANTIOSELECTIVE SYNTHESIS OF CHIRAL ALPHA-HYDROXYCARBOXYLATE BY REACTING A PROCHIRAL ALPHA-KETOCARBOXYLIC ACID WITH A SINGLE ENANTIOMER OF AN N-SUBSTITUTED VICINAL AMINOALCOHOL OF SPECIFIC CYCLOHYDROCARBONS TO FORM ALPHA-HYDROXYCARBOXYLATE SEPRACOR INC. (US) 2000-02-15 US claimed
WO-1999050205-A2 ASYMMETRIC GRIGNARD SYNTHESIS WITH CYCLIC 1,2 AMINOALCOHOLS SEPRACOR INC. (US) 1999-10-07 WO claimed
EP-0577302-B1 Process for preparing alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl sulfonates LILLY CO ELI (US) 1997-07-16 EP claimed
EP-0640614-B1 Stereoselective process for preparing beta-anomer enriched 2-deoxy-2, 2-difluoro-d-ribofuranosyl-3, 5-hydroxy protected-1-alkyl and aryl sulfonate intermediates LILLY CO ELI (US) 1996-12-04 EP claimed
US-5424416-A Sulfonating a lactol, followed with nucleobase anion, forming anomers ELI LILLY AND COMPANY (US) 1995-06-13 US claimed
EP-0640614-A2 Stereoselective process for preparing beta-anomer enriched 2-deoxy-2, 2-difluoro-d-ribofuranosyl-3, 5-hydroxy protected-1-alkyl and aryl sulfonate intermediates ELI LILLY AND COMPANY (US) 1995-03-01 EP claimed
EP-0577302-A1 Process for preparing alpha-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl sulfonates ELI LILLY AND COMPANY (US) 1994-01-05 EP claimed
US-5256798-A Treating beta-anomer ribofuranosyl sulfonate with source of conjugate anion ELI LILLY AND COMPANY (US) 1993-10-26 US claimed
US-5118836-A OPTICALLY ACTIVE FLUORINE-CONTAINING 3-HYDROXYBUTYRIC ACID ESTERS AND PROCESS FOR PRODUCING THE SAME SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1992-06-02 US claimed