Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2513076 | 0.98 | LMNA (0.31) | LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL2519648 | 0.80 | LMNA (0.33) | LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL375192 | 0.77 | HDAC8 (0.32) | — | |
| SCHEMBL372502 | 0.72 | HDAC8 (0.33) | — | |
| Bromide SCHEMBL710394 | 0.70 | ACHE (0.46) | CA1CA2LMNAHPGDHTT | |
| SCHEMBL2517053 | 0.70 | — | — | |
| SCHEMBL15670813 | 0.69 | ACHE (0.35) | LMNAHPGDHTTSMN1; SMN2 | |
| Bromide SCHEMBL1331596 | 0.68 | LMNA (0.50) | CA1CA2LMNAHPGDHTT | |
| SCHEMBL294564 | 0.68 | — | — | |
| SCHEMBL28394690 | 0.68 | ACHE (0.47) | CA1CA2LMNAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034956-B2 | Ionic liquid and method for producing the same, method for forming oxide film on metal surface, electrolyte capacitor and electrolyte | KANEKA CORPORATION (JP) | 2011-10-11 | — | — | US | disclosed |