SCHEMBL25143

SCHEMBL25143

O=C(O)CCCCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 1.00
HTT P42858 1/20 0.52
EPHX2 P34913 1/20 0.48
CASP3 P42574 2/20 0.46
HTR2C P28335 1/20 0.45
SLC6A3 Q01959 1/20 0.45
MAPK1 P28482 1/20 0.44
FABP7 O15540 1/20 0.44
FABP5 Q01469 1/20 0.44
TLR2 O60603 1/20 0.43
TLR1 Q15399 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL178895 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178890 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL2182769 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL17746959 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178762 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178760 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178759 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178761 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178758 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178892 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250352656-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS PEPTOMER THERAPEUTICS PRIVATE LTD (IN) 2025-11-20 US claimed
US-20250205372-A1 RADIOPHARMACEUTICAL COMPOSITIONS, SYNTHETIC METHODS, AND METHODS OF TREATMENT THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2025-06-26 US claimed
CN-119912519-A Double-target targeted polypeptide compound, preparation method and application 中国人民解放军总医院第一医学中心 2025-05-02 CN claimed
EP-4525827-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS Peptomer Therapeutics Private Limited (IN) 2025-03-26 EP claimed
WO-2023209728-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS PEPTOMER THERAPEUTICS PRIVATE LIMITED (IN) 2023-11-02 WO claimed
CN-116903495-A Preparation method of radioactive diagnostic drug ligand 江苏华益科技有限公司 2023-10-20 CN claimed
WO-2023178313-A2 RADIOPHARMACEUTICAL COMPOSITIONS, SYNTHETIC METHODS, AND METHODS OF TREATMENT THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-09-21 WO claimed
EP-1581486-B1 METHOD FOR ASSAYING COMPOUNDS THAT DECREASE THE ACTIVITY OF POLY(ADP-RIBOSE)-POLYMERASE (PARP) AVENTIS PHARMA INC (US) 2009-07-29 EP claimed
EP-1581486-A4 METHOD FOR ASSAYING COMPOUNDS THAT DECREASE THE ACTIVITY OF POLY(ADP-RIBOSE)-POLYMERASE (PARP) AVENTIS PHARMA INC (US) 2007-05-02 EP claimed
EP-1581486-A2 METHOD FOR ASSAYING COMPOUNDS THAT DECREASE THE ACTIVITY OF POLY(ADP-RIBOSE)-POLYMERASE (PARP) Aventis Pharmaceuticals, Inc. (US) 2005-10-05 EP claimed
CN-1675543-A Methods of detecting the ability of a compound or agent to decrease the activity of microsomal prostaglandin E synthase or hematopoietic prostaglandin D synthase AVENTIS PHARMA INC (US) 2005-09-28 CN claimed
EP-1543327-A2 METHOD FOR ASSAYING COMPOUNDS OR AGENTS FOR ABILITY TO DECREASE THE ACTIVITY OF MICROSOMAL PROSTAGLANDIN E SYNTHASE OR HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE Aventis Pharmaceuticals, Inc. (US) 2005-06-22 EP claimed
EP-1506970-A1 COMPOUNDS WHICH CAN BLOCK THE RESPONSE TO CHEMICAL SUBSTANCES OR THERMAL STIMULI OR MEDIATORS OF INFLAMMATION OF NOCICEPTORS, PRODUCTION METHOD THEREOF AND COMPOSITIONS CONTAINING SAME Diverdrugs, S.L. (ES) 2005-02-16 EP claimed
US-20040115710-A1 Method for assaying compounds that decrease the activity of poly (ADP-ribose)-Polymerase (PARP) AVENTIS PHARMACEUTICALS INC. (US) 2004-06-17 US claimed
US-20040082021-A1 Method for assaying compounds or agents for ability to decrease the activity of microsomal prostaglandin E synthase or hematopoietic prostaglandin D synthase AVENTIS PHARMACEUTICALS INC. 2004-04-29 US claimed
WO-2004026820-A2 METHOD FOR ASSAYING COMPOUNDS THAT DECREASE THE ACTIVITY OF POLY(ADP-RIBOSE)-POLYMERASE (PARP) AVENTIS PHARMACEUTICALS INC. (US) 2004-04-01 WO claimed
WO-2004016223-A2 ASSAYING COMPOUNDS OR AGENTS FOR MICROSOMAL PROSTAGLANDIN E SYNTHASE OR HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE ACTIVITY AVENTIS PHARMACEUTICALS INC. (US) 2004-02-26 WO claimed
EP-4735047-A1 PEGYLATED LINKERS AND USES THEREOF Université de Tours (FR) 2026-05-06 EP disclosed
WO-1989002439-A1 NON-NUCLEOTIDE LINKING REAGENTS FOR NUCLEOTIDE PROBES ML TECHNOLOGY VENTURES, L.P. (US) 1989-03-23 WO disclosed
EP-0225807-A2 Solution phase nucleic acid sandwich assay and polynucleotide probes useful therein CHIRON CORPORATION (US) 1987-06-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250352656-A1 SYNTHETIC CATIONIC PEPTIDOMIMETICS, THEIR DERIVATIVES AND PREPARATION THEREOF ALONG WITH COMPOSITIONS FOR VARIOUS MEDICAL APPLICATIONS NOD2, NGLY1, CGAS KMT2A 4744/4885HTT 211/4885EPHX2 2826/4885
US-20250205372-A1 RADIOPHARMACEUTICAL COMPOSITIONS, SYNTHETIC METHODS, AND METHODS OF TREATMENT QPCT, SSTR5, SSTR4 KMT2A 2814/4885HTT 321/4885EPHX2 2224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.