SCHEMBL178892

SCHEMBL178892

O=C(O)CCCCCCCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 1.00
HTT P42858 1/20 0.52
EPHX2 P34913 1/20 0.48
CASP3 P42574 2/20 0.46
HTR2C P28335 1/20 0.45
SLC6A3 Q01959 1/20 0.45
MAPK1 P28482 1/20 0.44
FABP7 O15540 1/20 0.44
FABP5 Q01469 1/20 0.44
TLR2 O60603 1/20 0.43
TLR1 Q15399 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL178895 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL25143 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178890 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL2182769 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL17746959 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178762 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178760 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178759 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178761 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C
SCHEMBL178758 1.00 KMT2A (1.00) KMT2AHTTEPHX2CASP3HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719498-A1 RADIOLIGANDS FOR TARGETING CELL SURFACE RECEPTORS AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP disclosed
EP-4719486-A1 CONJUGATES AND USES THEREOF Full-Life Technologies UK Limited (GB) 2026-04-08 EP disclosed
US-20260048157-A1 FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY PURDUE RESEARCH FOUNDATION (US) 2026-02-19 US disclosed
EP-4676538-A2 BI-SPECIFIC ADAPTERS AND THEIR USE WITH UNIVERSAL CAR-T CELLS IN THE TREATMENT OF CAIX-EXPRESSING TUMORS Purdue Research Foundation (US) 2026-01-14 EP disclosed
US-20260009799-A1 CA-IX TARGETING FLUORESCENT PROBES BRACCO IMAGING S.P.A. (IT) 2026-01-08 US disclosed
US-12508319-B2 Luteinizing hormone-releasing hormone receptor (LHRH-R) conjugates and uses thereof PURDUE RESEARCH FOUNDATION (US) 2025-12-30 US disclosed
EP-4663205-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF Shanghai Best-Link Bioscience, LLC (CN) 2025-12-17 EP disclosed
US-20250352675-A1 CA-IX TARGETING FLUORESCENT PROBES BRACCO IMAGING S.P.A. (IT) 2025-11-20 US disclosed
EP-4619411-A1 DUAL RECEPTOR TARGETING RADIOLIGANDS AND USES THEREOF Full-Life Technologies HK Limited (HK) 2025-09-24 EP disclosed
US-12377175-B2 Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies CORNELL UNIVERSITY (US) 2025-08-05 US disclosed
US-20040115774-A1 Polymer-modified synthetic proteins AMYLIN PHARMACEUTICALS, INC. 2004-06-17 US disclosed
CN-1460023-A Polymer modified bioactive synthetic chemokines and methods of production and use GRYPHON TREAT CO (US) 2003-12-03 CN disclosed
EP-1318827-A1 POLYMER-MODIFIED SYNTHETIC PROTEINS Gryphon Therapeutics, Inc. (US) 2003-06-18 EP disclosed
WO-2002020033-A1 POLYMER-MODIFIED SYNTHETIC PROTEINS GRYPHON THERAPEUTICS, INC. (US) 2002-03-14 WO disclosed
EP-0352249-B1 NOVEL PLATELET-AGGREGATION INHIBITORS Monsanto Company (US) 1993-09-08 EP disclosed
EP-0541663-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS HAVING GLYCOPROTEIN HORMONE AGONISTIC OR ANTAGONISTIC ACTIVITY STICHTING CENTRAAL DIERGENEESKUNDIG INSTITUUT (NL) 1993-05-19 EP disclosed
WO-1992002542-A1 PEPTIDES AND PHARMACEUTICAL COMPOSITIONS HAVING GLYCOPROTEIN HORMONE AGONISTIC OR ANTAGONISTIC ACTIVITY STICHTING CENTRAAL DIERGENEESKUNDIG INSTITUUT (NL) 1992-02-20 WO disclosed
US-4992463-A Thienyl peptide mimetic compounds which are useful in inhibiting platelet aggregation MONSANTO COMPANY (US) 1991-02-12 US disclosed
EP-0352249-A1 Novel platelet-aggregation inhibitors Monsanto Company (US) 1990-01-24 EP disclosed
US-4879313-A ANTICOAGULANTS MOSANTO COMPANY (US) 1989-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260009799-A1 CA-IX TARGETING FLUORESCENT PROBES CA9, CA12, CA1 KMT2A 2160/4885HTT 4701/4885EPHX2 455/4885
US-12508319-B2 Luteinizing hormone-releasing hormone receptor (LHRH-R) conjugates and uses thereof LHCGR, GNRHR, SSTR1 KMT2A 2359/4885HTT 2159/4885EPHX2 2635/4885
US-12377175-B2 Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies VHL, GLS, GPER1 KMT2A 3904/4885HTT 3352/4885EPHX2 2470/4885
US-20260048157-A1 FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY FAP, FIBP, FGFR1 KMT2A 3796/4885HTT 3730/4885EPHX2 2002/4885
US-20250352675-A1 CA-IX TARGETING FLUORESCENT PROBES CA9, CA4, CA7 KMT2A 2697/4885HTT 4754/4885EPHX2 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.