Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | FADS1 | O60427 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | BLK | P51451 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6106401 | 0.84 | FADS1 (0.59) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL15882332 | 0.83 | NPC1 (0.60) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL31110119 | 0.82 | NPC1 (0.70) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL4853468 | 0.82 | NPC1 (0.70) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL14314287 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL12276900 | 0.79 | NPC1 (0.51) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL31665640 | 0.79 | KMT2A (0.50) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL25142640 | 0.79 | KMT2A (0.50) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL25142977 | 0.78 | FADS1 (0.55) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL13543517 | 0.77 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023061440-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2023-04-20 | — | — | WO | disclosed |