Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 9/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25144071 | 0.88 | P2RX7 (0.53) | ANO1CA1CA2P2RX7KDM4E | |
| SCHEMBL23619811 | 0.83 | P2RX7 (0.51) | ANO1P2RX7 | |
| SCHEMBL25144075 | 0.81 | POLB (0.55) | ANO1CA1CA2KDM4EPOLB | |
| SCHEMBL24685984 | 0.81 | P2RX7 (0.49) | ANO1P2RX7KDM4E | |
| SCHEMBL25144074 | 0.81 | SMN1; SMN2 (0.53) | ANO1POLB | |
| SCHEMBL24713219 | 0.79 | P2RX7 (0.48) | ANO1P2RX7POLB | |
| SCHEMBL9926581 | 0.79 | CA1 (0.48) | ANO1CA1CA2P2RX7KDM4E | |
| SCHEMBL21198322 | 0.78 | ANO1 (1.00) | ANO1 | |
| SCHEMBL31306605 | 0.78 | ANO1 (1.00) | ANO1 | |
| SCHEMBL10989847 | 0.78 | ANO1 (0.57) | ANO1CA1CA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230118751-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230118751-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | P2RX4, P2RX3, P2RX2 | ANO1 1344/4885CA1 787/4885CA2 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.