Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 7/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31239638 | 1.00 | ALOX5AP (0.36) | ALOX5APFEN1GPR119CNR2CNR1 | |
| SCHEMBL25325345 | 0.76 | ABHD6 (0.40) | ALOX5APFEN1GPR119ABHD6FAAH | |
| SCHEMBL25325348 | 0.76 | ABHD6 (0.40) | ALOX5APFEN1GPR119ABHD6FAAH | |
| SCHEMBL25145962 | 0.76 | CNR2 (0.36) | CNR2CNR1 | |
| SCHEMBL31239653 | 0.76 | CNR2 (0.36) | CNR2CNR1 | |
| SCHEMBL30410134 | 0.76 | MGLL (0.43) | ABHD6FAAHMGLL | |
| SCHEMBL25146290 | 0.76 | MGLL (0.43) | ABHD6FAAHMGLL | |
| SCHEMBL29427117 | 0.72 | DDB1 (0.44) | ABHD6FAAHMGLL | |
| SCHEMBL26631392 | 0.72 | DDB1 (0.44) | ABHD6FAAHMGLL | |
| SCHEMBL27246542 | 0.70 | PTGDR2 (0.35) | CNR2CNR1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |