⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25146 | 0.77 | — | — | |
| SCHEMBL16018282 | 0.70 | — | — | |
| SCHEMBL9843077 | 0.70 | — | — | |
| SCHEMBL1391357 | 0.69 | — | — | |
| SCHEMBL1146068 | 0.65 | — | — | |
| SCHEMBL10716728 | 0.65 | — | — | |
| SCHEMBL1117784 | 0.65 | — | — | |
| SCHEMBL1059438 | 0.64 | — | — | |
| SCHEMBL8741525 | 0.64 | — | — | |
| SCHEMBL10087269 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753638-B2 | Conjugated oligonucleotides | UNIVERSITY OF MASSACHUSETTS (US) | 2023-09-12 | — | — | US | disclosed |
| US-20190185855-A1 | CONJUGATED OLIGONUCLEOTIDES | UNIVERSITY OF MASSACHUSETTS | 2019-06-20 | — | — | US | disclosed |
| WO-2018031933-A2 | CONJUGATED OLIGONUCLEOTIDES | UNIVERSITY OF MASSACHUSETTS (US) | 2018-02-15 | — | — | WO | disclosed |
| US-20170043024-A1 | BIOACTIVE CONJUGATES FOR OLIGONUCLEOTIDE DELIVERY | UNIVERSITY OF MASSACHUSETTS | 2017-02-16 | — | — | US | disclosed |