Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6066072 | 0.91 | HSD11B1 (0.34) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL6065777 | 0.90 | HSD11B1 (0.34) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL6065798 | 0.88 | HSD11B1 (0.33) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL2512967 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL6065035 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL6064955 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6065071 | 0.82 | HSD11B1 (0.34) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL2516048 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL6065938 | 0.81 | HSD11B1 (0.34) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL6065605 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034886-B2 | Process for manufacturing high to ultra high molecular weight polymers using novel bridged metallocene catalysts | TICONA GMBH (DE) | 2011-10-11 | — | — | US | disclosed |
| US-20100056737-A1 | Process for manufacturing high to ultra high molecular weight polymers using novel bridged metallocene catalysts | NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7598329-B2 | Process for manufacturing ultra high molecular weight polymers using novel bridged metallocene catalysts | TICONA GMBH (DE) | 2009-10-06 | — | — | US | disclosed |
| US-20070105712-A1 | Process for manufacturing ultra high molecular weight polymers using novel bridged metallocene catalysts | NUTRINOVA NUTRITION SPECIALTIES & FOOD INGREDIENTS GMBH (DE) | 2007-05-10 | — | — | US | disclosed |