Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 4/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409361 | 0.91 | MGLL (0.43) | MGLLCHRM1SPRLIPEAKR1C3 | |
| SCHEMBL25145990 | 0.85 | CHRM1 (0.44) | MGLLCHRM1SPRLIPEAKR1C3 | |
| SCHEMBL25146250 | 0.83 | MGLL (0.46) | MGLLSPRLIPEMEN1KMT2A | |
| SCHEMBL25146248 | 0.82 | SCN9A (0.47) | MGLLAKR1C3MEN1KMT2AALDH1A1 | |
| SCHEMBL18711904 | 0.76 | CHRM1 (0.54) | CHRM1SPRLIPEAKR1C3MEN1 | |
| SCHEMBL18702270 | 0.75 | CHRM1 (0.53) | CHRM1SPRLIPEAKR1C3MEN1 | |
| SCHEMBL30409535 | 0.75 | CHRM1 (0.40) | MGLLCHRM1SPRLIPEAKR1C3 | |
| SCHEMBL30408615 | 0.74 | DPP4 (0.41) | MGLLSPRLIPEAKR1C3MEN1 | |
| SCHEMBL30408465 | 0.74 | SCN9A (0.41) | MGLLAKR1C3MEN1KMT2AKDM2B | |
| SCHEMBL25145978 | 0.72 | MGLL (0.46) | MGLLAKR1C3RORCDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |