Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SPR | P35270 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 7/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30409535 | 0.91 | CHRM1 (0.40) | CHRM1SPRLIPEMGLLAKR1C3 | |
| SCHEMBL25146128 | 0.85 | MGLL (0.49) | CHRM1SPRLIPEMGLLAKR1C3 | |
| SCHEMBL25145896 | 0.84 | MEN1 (0.43) | SPRLIPEMGLLMEN1KMT2A | |
| SCHEMBL25145889 | 0.83 | MGLL (0.48) | MGLLAKR1C3MEN1KMT2AALDH1A1 | |
| SCHEMBL30409361 | 0.76 | MGLL (0.43) | CHRM1SPRLIPEMGLLAKR1C3 | |
| SCHEMBL18711904 | 0.75 | CHRM1 (0.54) | CHRM1SPRLIPEAKR1C3MEN1 | |
| SCHEMBL30409598 | 0.74 | MGLL (0.41) | LIPEMGLLAKR1C3MEN1KMT2A | |
| SCHEMBL18702270 | 0.74 | CHRM1 (0.53) | CHRM1SPRLIPEAKR1C3MEN1 | |
| SCHEMBL30409945 | 0.73 | MGLL (0.48) | MGLLAKR1C3 | |
| SCHEMBL25145596 | 0.73 | L3MBTL1 (0.42) | MGLLALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023062049-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-04-20 | — | — | WO | disclosed |