Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 3/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1694215 | 1.00 | SLC1A3 (0.43) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL5324078 | 0.85 | SLC1A3 (0.40) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL136413 | 0.83 | CHRM1 (0.46) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL9678433 | 0.83 | CHRM1 (0.52) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| Hydrochloric Acid SCHEMBL19371377 | 0.81 | CHRM1 (0.50) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL11143927 | 0.81 | SLC7A5 (0.52) | SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL11771843 | 0.81 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL28051218 | 0.81 | — | — | |
| SCHEMBL13761133 | 0.80 | TDP1 (0.50) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 | |
| SCHEMBL1604267 | 0.80 | TDP1 (0.50) | SLC1A3SLC1A2SLC1A1TDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | PPID, PPIF, PPIL1 | SLC1A3 3251/4885SLC1A2 3284/4885SLC1A1 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.