Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIE | Q9UNP9 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25146438 | 0.95 | PPIE (0.89) | PPIE | |
| SCHEMBL25146784 | 0.95 | PPIE (0.89) | PPIE | |
| SCHEMBL23512450 | 0.92 | PPIE (0.90) | PPIE | |
| SCHEMBL23512749 | 0.92 | PPIE (0.86) | PPIE | |
| SCHEMBL25146555 | 0.92 | PPIE (0.85) | PPIE | |
| SCHEMBL23512574 | 0.92 | PPIE (0.85) | PPIE | |
| SCHEMBL23512636 | 0.92 | PPIE (0.85) | PPIE | |
| SCHEMBL23512516 | 0.92 | PPIE (0.86) | PPIE | |
| SCHEMBL25146573 | 0.92 | PPIE (0.88) | PPIE | |
| SCHEMBL23512507 | 0.91 | PPIE (0.83) | PPIE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | THE BROAD INSTITUTE, INC. (US) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117680-A1 | CYCLOPHILIN D INHIBITORS AND USES THEREOF | PPID, PPIF, PPIL1 | PPIE 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.