SCHEMBL25147290

SCHEMBL25147290

c1ccc(-c2nc(-c3ccccc3)c3c(n2)oc2cc4c5ccccc5n(-c5nc(-c6ccccc6)c6ccccc6n5)c4cc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
KDM4E B2RXH2 3/20 0.39
MAPT P10636 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KMT2A Q03164 5/20 0.39
MEN1 O00255 4/20 0.39
ATM Q13315 2/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
LMNA P02545 1/20 0.37
WHR1 P49842 1/20 0.34
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NUDT1 P36639 3/20 0.32
ADORA2A P29274 2/20 0.32
NPC1 O15118 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25146848 0.96 ALDH1A1 (0.39) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL25147302 0.93 MEN1 (0.34) KMT2AMEN1ATMLMNAWHR1
SCHEMBL25147309 0.88
SCHEMBL25146843 0.87 MEN1 (0.36) KMT2AMEN1ATMWHR1NPC1
SCHEMBL25146845 0.87 MEN1 (0.36) KMT2AMEN1ATMWHR1NPC1
SCHEMBL25147479 0.85 ALDH1A1 (0.40) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL25147301 0.83 NPSR1 (0.40) ALDH1A1HPGDMAPTNPSR1KMT2A
SCHEMBL25147242 0.83 SMN1; SMN2 (0.32) KDM4EKMT2AMEN1ATML3MBTL1
SCHEMBL25147151 0.83 ATM (0.34) ALDH1A1KDM4ENPSR1KMT2AMEN1
SCHEMBL17990801 0.82 ALDH1A1 (0.41) ALDH1A1HPGDKDM4EMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023061998-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-04-20 WO disclosed